Overview | Sophora flavescens is the dried root of Sophora flavescens Sophora flavescens. First in the Han Dynasty Shen Nong Herbal, as a product, in more than 2000 years of clinical practice has played a number of effects. With heat dampness, insecticidal, diuretic function. Clinically used for hot dysentery, blood in the stool, jaundice, urine closed, red under the leucorrhea, Yin and itching, eczema, wet sores, skin itching, scabies leprosy; External treatment of Trichomonas vaginitis. |
pharmacological effects | Sophora flavescens has the following pharmacological activities: anti-tumor effect, anti-inflammatory and antibacterial effect, antiviral effect, immunomodulatory effect, anti-liver injury, anti-allergic and anti-asthma, hypoglycemic, inhibition of enzyme, inhibition of central nervous system; In addition, matrine and flavanones in Sophora flavescens have obvious protective effect on gastric mucosal injury, its isopentenyl dihydroflavonoids have anti-androgenic hormone-like effects; Sophora flavescens has anti-parasitic, in vitro spermicidal, diuretic, cholagogic, antidiarrheal and other pharmacodynamic effects. Sophora flavescens is mainly composed of alkaloids and flavonoids. Alkaloids are the main active ingredients of Sophora flavescens, 34 kinds of alkaloids have been isolated from them (including quinolicidine, cystuline type, pyronine type, lupine type and dipiperidine), which content is higher, the activity of strong for oxymatrine, matrine, oxysophocarpine, Sophora flavescens alcohol E. |
biological activity | Kushenol E is a class of flavonoids isolated from slora flavescens and is a non-competitive inhibitor of ido1, its IC50 value is 7.7 μm, Ki value is 9.5 μm, has anti-tumor activity. |
Use | anti-oxidation, anti-tumor. |